Pesquisa sobre: PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 12 
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Descritor Inglês:   Protein Tyrosine Phosphatase, Non-Receptor Type 12 
Descritor Espanhol:   Proteína Tirosina Fosfatasa no Receptora Tipo 12 
Descritor Português:   Proteína Tirosina Fosfatase não Receptora Tipo 12 
Sinônimos Inglês:   PEP PTPase
PEP Protein Tyrosine Phosphatase
PEST Enriched Phosphatase
PEST-Enriched Phosphatase
PTP-PEST
PTPase, PEP
Phosphatase, PEST-Enriched
Protein Tyrosine Phosphatase, Non Receptor Type 12  
Categoria:   D08.811.277.352.650.775.300.850
D12.644.360.585.850
D12.776.476.564.850
Definição Inglês:   A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of a N-terminal catalytic domain and a large C-terminal domain that is enriched in PROLINE, GLUTAMIC ACID, SERINE, and THREONINE residues (PEST sequences). The phosphatase subtype is ubiquitously expressed and implicated in the regulation of a variety of biological processes such as CELL MOVEMENT; CYTOKINESIS; focal adhesion disassembly; and LYMPHOCYTE ACTIVATION. 
Nota Histórica Inglês:   2008(1994) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   52701 
Identificador Único:   D054594 

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